Supporting Information Multiplexed DNA-Modified Electrodes

Multiplexed DNA-modified electrodes.

We report the use of silicon chips with 16 DNA-modified electrodes (DME chips) utilizing DNA-mediated charge transport for multiplexed detection of DNA and DNA-binding protein targets. Four DNA sequences were simultaneously distinguished on a single DME chip with 4-fold redundancy, including one incorporating a single base mismatch. These chips also enabled investigation of the sequence-specifi...

ELECTROCHEMICAL BEHAVIOR OF GC, Pt AND Au ELECTRODES MODIFIED WITH THIN FILM OF COBALT HEXACYANOFERRATE

0A thin film of cobalt hexacyanoferrate (CoHCF), an analogue of mixed-valence Prussian blue, was deposited electrochemically on the glassy carbon, platinum and gold electrode surfaces in 0.5M KC1 solution. The electrochemical behavior of these modified electrodes show three couples of redox peaks by CV in a supporting electrolyte solution of 0.5M NaCl, whereas for Au modified electrode only ...

Multiplexed electrochemistry of DNA-bound metalloproteins.

Here we describe a multiplexed electrochemical characterization of DNA-bound proteins containing [4Fe-4S] clusters. DNA-modified electrodes have become an essential tool for the characterization of the redox chemistry of DNA repair proteins containing redox cofactors, and multiplexing offers a means to probe different complex samples and substrates in parallel to elucidate this chemistry. Multi...

Supporting Information Intravenous Implantable Glucose/Dioxygen Biofuel Cell with Modified Flexible Carbon Fiber Electrodes

Direct DNA hybridization at disposable graphite electrodes modified with carbon nanotubes.

The performance of glassy carbon (GCE) and graphite pencil electrodes (PGE) modified with multiwalled carbon nanotubes (CNTs) are compared, based on the direct electrochemical detection of nucleic acids. This is accomplished by monitoring the differential pulse voltammetry changes of the guanine signal. CNT-modified PGE compares favorably to that of the commonly used CNT-modified GCE owing to t...